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Immunotherapy

‘Boosting a cancer patient’s immune system’


Immunotherapy, used in cancer treatment for decades, focuses on boosting the body’s immune system
which is often ravaged by cancer-treatment and its side-effects. It is an option for many common
cancers like bladder, breast, cervical, brain tumor, kidney, liver, head, neck, colon, etc. The best thing
about this therapy is the continuous research in this field which means new and better ways to combat
cancer. It has fewer harmful effects as compared to conventional treatments like chemotherapy and
radiation therapy. Essentially this approach utilizes the power of the immune system against cancer.

In other words it’s a relatively new type of cancer treatment which uses medicine to boost a patients
immune system. Such treatments work across different types of cancer and are used in even extremely
complex cases.


Immunotherapy uses a persons natural immune system to combat a cancer. It could boost existing characteristics in the immune system or make medication that has features of ones immune system which can then help fight the cancer. It involves the infusion of large doses of proteins into the patients system. This in turn leads to the production of more immune cells which can resist the disease as well as target cancer cells.


John Hopkins Institute researchers say an immunotherapy drug can be just as effective if not more than conventional drugs in treating say, Merkel cell carcinoma.

immunotherapy

Immunotherapy is administered via an intravenous infusion into the blood stream of the patient. It is used in the treatment of many cancers like leukemia, lymphoma, skin, prostate, lung, liver, colon, breast and colon.


Using the bodys immune system to battle cancer is a promising treatment which is bound to grow and develop further in the future.
 

Some of immunotherapies provided are (courtesy: my.clevelandclinic.org)

 

  • Adoptive cell therapy

  • Vaccines

  • Immunomodulators

  • Monoclonal antibodies

  • Incolytic viruses

 

In other words it’s a relatively new type of cancer treatment which uses medicine to boost a patients
immune system. Such treatments work across different types of cancer and are used in even extremely
complex cases.


Immunotherapy uses a persons natural immune system to combat a cancer. It could boost existing characteristics in the immune system or make medication that has features of ones immune system which can then help fight the cancer. It involves the infusion of large doses of proteins into the patients system. This in turn leads to the production of more immune cells which can resist the disease as well as target cancer cells.


John Hopkins Institute researchers say an immunotherapy drug can be just as effective if not more than conventional drugs in treating say, Merkel cell carcinoma.

In ‘Precision Medicine’ the goal is to provide relief for patients through individualised care. This is in
stark contrast to earlier approaches when chemotherapy and radiation would damage surrounding
healthy tissue along with cancerous tissue. Precision medicine is the bedrock of Immunotherapy and
results from a wide range of cancers treated by Immunotherapy, are very encouraging.
(Hopkinsmedicine.org)


A decade ago, a team led by Suzanne Topalian of Bloomberg-Kimmel Institute of Cancer Immunotherapy
found that many cancers & put the brakes on the body's immune cells that would normally attack a
tumor and destroy it. They discovered a class of drugs called "immune checkpoint blockers that took
the brakes off the immune system thereby giving it a chance to fight back against the cancer.

Immunotherapy has shown success in several types of cancers including lung, head, neck, bladder and
kidney. The Immunotherapy drug named pembrolizumab used as first-line therapy showed encouraging
results on patients compared to those who got chemotherapy. When former US President Jimmy Carter
was diagnosed with metastatic melanoma in his brain and liver he received combination therapy
including the Immunotherapy drug pembrolizumab.


Immunotherapy could be poised to be used on a larger scale once researchers and scientists at
University of Geneva UNIGE and Harvard Medical School establish "differences between deleterious
immune reactions and those targeting tumor cells." Their significant work was published in "Science
Immunology" and bodies well for better targeted more effective treatments (sciencedaily.com)

 


There are many types of immunotherapy. These include:

 

  • Monoclonal antbodies and tumor-agnostic treatments such as checkpoint inhibitors

  • Oncolytic virus therapy

  • T cell therapy


The type of drug dose and treatment schedule will depend upon many factors: type of cancer, size,
location and where it has spread. Age, general health, body weight and how well (one) can cope with
side effects are important. Monoclonal antibodies are made in a laboratory to boost (the) body’s natural
antibodies. They can be used to block the activity of abnormal proteins in cancer cells (called “targeted
therapy”).


Oncolytic virus therapy uses the viruses that have been changed in a laboratory to destroy cancer cells.
The doctor injects the genetically modified virus into the tumor. The virus enters the cancer cell and
makes a copy of itself, but does not enter healthy cells.

Homeopathy

The word homeopathy is a compound of two words homoios (similar) and pathos (suffering). It is a recognized medical system in India through the Homeopathy Central Council Act, 1973 and draws on several strong traditions in the country and is recognized as “one of the national systems of medicine”.

The basic principle of homeopathy is that a substance that triggers a certain disease can also be used to treat that disease. This is referred to as the “Law of Similars”. The principle of Similia Similibus Curantur, which demonstrates that a remedy selected for the treatment of a natural disease shall be the one that is capable of producing a range of similar symptoms in a healthy person.

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Basically, this principle demonstrates that disease can be cured by a medicinal substance that is tested on the principles of Homeopathic pharmacodynamics.

 

In the introduction of “The Theory of Chronic diseases”, 1828, Dr. Hahnemann presented the method of using acute and chronic incurrent remedies. It is usually prescribed where the indicated remedy works well for a while and then begins to taper off. It can be in the form of a nosode, a complementary, or constitutional  remedy.

Introduced in India in the early 19th century, homeopathy was created and practiced by Dr Christian Friedrich Samuel Hahnemann (1755-1843), the German physician whose principle ‘like cures like’ became the basis of the alternate medicine. His first medical school founded in the US in the late 1880s successfully treated many epidemics – like typhoid, scarlet fever, cholera and yellow fever.

 

Homeopathy came to India in 1810 with a Frenchman Dr John Martin Honigberger who on a visit to India treated Maharaja Ranjit Singh with a homeopathic remedy Dulcamara when he was suffering from paralysis of the vocal cords.  The results were impressive enough for the Maharaja to encourage Dr Martin to continue practicing in India. The first hospital and clinic was established in Calcutta 1851 from where the practice spread to other parts of India. In 1973 the Govt of India recognized it as a national medicinal system, supporting its training and distribution. The CCH (Central Council of Homeopathy was established as a regulatory role to impact its education and practice. Homeopathy’s popularity in India stems from its effectiveness, low-costs and safety.

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Among various other disorders, homeopathy has been used for helping alleviate conditions like allergy, dengue, lifestyle disorder, nutritional disorder, kidney stone, swine flu, asthma, diabetes, mouth ulcers.

Homoeopathic Pharmacopoeia of India (HPI) is the official book of standards of Homeopathic medicine in terms of Schedule-II of the Drugs and Cosmetics Act, l940 and Rules, l945. Indian manufacturers are legally bound to manufacture Homoeopathic medicines as per standards and methodology given in the Homoeopathic Pharmacopoeia of India.

The source of Homoeopathic drugs is mostly of natural origin viz. vegetables/plants, animals, minerals, chemicals, Nosodes, Sarcodes etc. For this purpose the Committee has experts from the Chemistry, Botany, Microbiology / Pharmacology besides manufacturers of Homoeopathic medicine and eminent homoeopaths as well as officials who are concerned with the work of testing and research in drugs.

The HPI is prepared by the Homeopathic Pharmacopeia Committee (HPC) constituted by the Government of India with the following objectives:

  1. To prepare Pharmacopoeia of Homoeopathic drugs whose therapeutic usefulness have been proved on the lines of the American, German and British Homoeopathic Pharmacopoeias;

  2. To lay down principles and standards for the preparation of Homoeopathic drugs;

  3. To lay down test of identity, quality, purity; and

  4. Such other matters as are incidental and necessary for the preparation of a Homoeopathic Pharmacopoeia.

 

Courtesy: www.nhp.gov.in

Homeopaths follow several approaches in their prescriptions: acute, aetiological, keynote, constitutional, intercurrent, miasmatic, nosological, organopathic, pathological, synthetic, palliative. Even the patient is not personally present for consultation the medicines can be prescribed  based on the diagnostic evidences.

In Homeopathy, the most appropriate treatment protocol is based on the simila principle; however, this may not happen in all the cases. This is because in certain cases there may not be adequate symptom to select the similimum, or in certain cases  already  other mode of treatment might have been applied and the true picture  might be masked. There may also be instances the case may be at an incurable stage, which may warrant only palliation. Therefore, planning the course of treatment may not always be on a fixed protocol. Experienced physicians switch from one method to another based on the case, availability of the symptoms and also based on his experience. 


 

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The basic objective is to find out a closest similmum to the patients totality of symptoms as perceived by the physician. Sometimes physicians may get a clue about the similmum with one or two symptoms, in another case he may have to take full case history to get the totality. Even in such cases if the physician is not able to arrive at a similimum, he may evaluate the background, past history etc to get a more accurate prescription.

Homeopathic products are derived from plants such as red onion, arnica (mountain herb), poison ivy, belladonna (deadly nightshade), stinging nettle, minerals (such as white arsenic), or crushed whole bees. Medicinal plants include Gingko, Turmeric, Evening primrose oil, Flax seed, Tea tree oil, Echinacea, Grapeseed extract, Lavender. Homeopathy medicine names are derived from substances – some common names are horse-chestnut, aloe, marigold, squirting cucumber, sundew and marsh tea.

A medicinal system in which natural substances like plants and minerals are diluted to prepare medicines that trigger the body’s own healing mechanisms and activate natural defences in the body. Administered in very minute doses, homeopathy medicines can be taken orally and are safe and non- toxic. These medicines do not lower immune resistance nor do they trigger allergic reactions and are often prescribed for acute and chronic conditions.

homeopathy

“Integrative Treatment” Immunotherapy & Homeopathy

Sanjeevan Onco Care embraces the modern line of thinking that cancer treatment needs a twin-pronged approach: one, the starving and destruction of cancerous cells and two, a food-based boosting of the immune system during and after cancer-therapy. 

Treatments custom-made to a patient’s needs are advised by registered professional medical practitioners of homeopathy. These treatments are food-based and play multiple roles e.g. build up blood vessels, get rid of cancer stem cells, boost DNA and enhance useful bacteria in the human body.

ANTI - ANGIOGENESIS

What is Angiogenesis?

Sixty thousand miles of blood vessels course throughout our bodies and bring oxygen and nutrients to all of our cells and organs. Angiogenesis is the growth of blood vessels from the existing vasculature. It occurs throughout life in both health and disease, beginning in utero and continuing on through old age. No metabolically active tissue in the body is more than a few hundred micrometers from a blood capillary, which is formed by the process of angiogenesis. Capillaries are needed in all tissues for diffusion exchange of nutrients and metabolites.

Changes in metabolic activity lead to proportional changes in angiogenesis and, hence, proportional changes in capillarity. Oxygen plays a pivotal role in this regulation. Hemodynamic factors are critical for survival of vascular networks and for structural adaptations of vessel walls.​

 

Recognition that control of angiogenesis could have therapeutic value has stimulated great interest during the past 40 years. Stimulation of angiogenesis can be therapeutic in ischemic heart disease, peripheral arterial disease, and wound healing. Decreasing or inhibiting angiogenesis can be therapeutic in cancer, ophthalmic conditions, rheumatoid arthritis, and other diseases. Capillaries grow and regress in healthy tissues according to functional demands. Exercise stimulates angiogenesis in skeletal muscle and heart. A lack of exercise leads to capillary regression. Capillaries grow in adipose tissue during weight gain and regress during weight loss. Clearly, angiogenesis occurs throughout life.

REGENERATION

Regeneration means the regrowth of a damaged or missing organ part from the remaining tissue. Powered by more than 750,000 stem cells distributed throughout our bone marrow, lungs, liver, and almost all of our organs, our body regenerates itself every day. If part of the liver is lost by disease or injury, the liver grows back to its original size, though not its original shape. And our skin is constantly being renewed and repaired. These stem cells maintain, repair, and regenerate our bodies throughout our lives. Nutritional value of some foods can mobilise the body and help us regenerate. 

MICROBIOMES

There are trillions of microorganisms, primarily bacteria,  living in our body that help defend our health. Together these are dubbed the human microbiota. Microbiota stimulate the immune system, break down potentially toxic food compounds, and synthesize certain vitamins and amino acids, including the B vitamins and vitamin K. For example, the key enzymes needed to form vitamin B12 are only found in bacteria, not in plants and animals.

Starting from mental health to digestion issues, our cutting edge Microbiome research and treatment has already been revolutionary for our patients.

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DNA

DNA PROTECTION

Our DNA is what makes us who we are. It is not only our genes but is designed to be our line of defense against illness’ that can eventually be life threatening. Food can be a strong catalyst in DNA protection but certain items can also degrade it. Our team of doctors treats each patient depending on their background and what problem they are facing specially when it comes to protecting something so unique like our DNA.

“Integrative Treatment” Immunotherapy & Homeopathy
angiogenesis
regeneration
microbiomes
dna protection
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